The main purpose of our lab is to recognize the effects of multiparity and ageing in cells and extracellular matrix during postpartum recovery at birth canal (pubic symphysis, uterine cervix and vagina) in mice. We pay particular interest to understand how birth and ageing have a significant effect in tissue homeostasis, which could help us to understand the pathophysiology of pelvic organ prolapse, urinary incontinence and preterm. We focus on the connective tissue - an important site of cellular, molecular and hormonal signaling - and ask how this tissue responds (or not) to changes during and after first and multiple pregnancies. Using morphological, biochemical and molecular assays, we identified that recovery processes are regulated by cells and molecules in the birth canal and multiparity and ageing led them to not recover in the reproductive matrix mice.
My research focusses on how plant traits affect the interactions between plants and insects. I am particularly interested in how plant traits change after interactions with herbivores and how these changes can influence the structure of natural and agricultural communities.
The research activities undertaken at our laboratory aim to study the Biochemistry of trypanosomatids, especially Trypanosoma cruzi, with emphasis on their bioenergetics and antioxidant mechanisms. We also test potential compounds to develop a more specific and less toxic therapy for Chagas disease.