Agenda IB
Silmara Marques Allegretti
We work with 3 main research topics in the Field of parasitic diseases caused by helmintic parasites (emphasis on Schistosoma mansoni, Strongyloides stercoralis e Angiostrongylus cantonensis and their vectors):
-Research of new drugs for treatment of helminthiasis;
-Study of wild and domestic animals parasitic diseases;
-Proteomic studies of helminthes and/or their vectors.
Elizabeth Bilsland
The current COVID-19 pandemic highlighted the vulnerability of our society to infections diseases. Whilst the current media focus is centered on SARS-CoV2, we must be prepared for the threat posed by drug-resistant parasites, fungi, and bacteria. The Synthetic Biology Laboratory (LaBS) was established in 2016 and is based on synthetic biology as a tool for drug discovery, using yeast and bacteria as hosts for heterologous expression and a platform for genome-wide screens. We have 3 well-established lines of investigation, which can further be improved and rapidly yield results. We are also introducing a novel highly ambitious line of research, taking advantage of our strong international collaboration network, for the development of novel antimicrobials inspired by secondary metabolites from native actinomycetes, filamentous fungi, or plant species.
Elaine Minatel
Leader of the Muscular Plasticity research group, developing works that evaluate the morphofunctional and molecular aspects, and behavior of skeletal muscle fibers 'in vitro and in vivo' under various experimental conditions, using histochemical, biochemical, immunofluorescence and molecular biology.