Agenda IB
Helena Coutinho Franco de Oliveira
We have focused on the role of plasma lipoprotein metabolism and associated proteins particularly relevant for the development of atherosclerosis, diabetes and obesity. Hormonal, nutritional and pharmacological regulation of key proteins involved in the metabolism of plasma lipoproteins are investigated with the goal of elucidating molecular mechanisms and putative therapeutic targets for cardio-metabolic disturbances.
Eneida de Paula
Biochemical pharmacology and pharmaceutical technology: 1) Development and characterization of drug-delivery systems in carriers such as cyclodextrins, liposomes, Nanostructured lipid carriers; 2) Biochemistry and Biophysics applied to the study of amphiphile interaction with biomimetic systems.
Fernanda Ramos Gadelha
The research activities undertaken at our laboratory aim to study the Biochemistry of trypanosomatids, especially Trypanosoma cruzi, with emphasis on their bioenergetics and antioxidant mechanisms. We also test potential compounds to develop a more specific and less toxic therapy for Chagas disease.