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Publications

  • Dos Reis Araujo T, Davel AP, Carneiro EM. Life-long health consequences of undernutrition in the Yanomami indigenous population in Brazil. Nat Med. 2024 Apr 30.  doi: 10.1038/s41591-024-02991-y

  • Victorio JA, Barssotti L, Aprahamian T, Costa RG, Mousovich-Neto F, Oliveira HCF, Mori M, Rossoni LV, Davel AP. β-Adrenergic Stimulation-Induced PVAT Dysfunction in Male Sex: A Role for 11β-Hydroxysteroid Dehydrogenase-1. Endocrinology. 2024 Apr 29;165(6):bqae053. doi: 10.1210/endocr/bqae053

  • Lazaro CM, Victorio JA, Davel AP, Oliveira HCF. CETP expression ameliorates endothelial function in female mice through estrogen receptor-α and endothelial nitric oxide synthase pathway. Am J Physiol Heart Circ Physiol. 2023 Sep 1;325(3):H592-H600. doi: 10.1152/ajpheart.00365.2023

  • Sousa AS, Passos MP, Ruberti OM, Jarrete AP, Delbin MA. Evaluation of coronary function in female rats with severe type 1 diabetes: Effects of combined treatment with insulin and pyridoxamine. Microvasc Res. 2023 Mar;146:104474. doi: 10.1016/j.mvr.2022.10447 

  • Freitas IN, da Silva JA Jr, de Oliveira KM, Lourençoni Alves B, Dos Reis Araújo T, Camporez JP, Carneiro EM, Davel AP. Insights by which TUDCA is a potential therapy against adiposity. Front Endocrinol (Lausanne). 2023 Feb 21;14:1090039. doi: 10.3389/fendo.2023.1090039. 

  • de Oliveira MG, Monica FZ, Passos GR, Victorio JA, Davel AP, Oliveira ALL, Parada CA, D'Ancona CAL, Hill WG, Antunes E. Selective Pharmacological Inhibition of NOX2 by GSK2795039 Improves Bladder Dysfunction in Cyclophosphamide-Induced Cystitis in Mice. Antioxidants (Basel). 2022 Dec 30;12(1):92. doi: 10.3390/antiox12010092. 

  • Peres EC, Victorio JA, Nunes-Souza V, Breithaupt-Faloppa AC, Rabelo LA, Tavares-de-Lima W, Davel AP, Rossoni LV. Simvastatin protects against intestinal ischemia/reperfusion-induced pulmonary artery dysfunction. Life Sci. 2022 Oct 1;306:120851. doi: 10.1016/j.lfs.2022.120851.  

  • Silva TQAC, Delbin MA. Takotsubo Syndrome: Special Attention to Women's Health. Braz J Cardiovasc Surg. 2022 Oct 8;37(5):792. doi: 10.21470/1678-9741-2022-0312.  

  • Jarrete AP, Giollo-Junior LT, Vilela-Martin JF, Novais IP, Delbin MA, Zanesco A. Alterations in pro- and anti-inflammatory mediators are involved in microvascular dysfunction in postmenopausal women with type 2 diabetes mellitus. Braz J Med Biol Res. 2022 Feb 28;55:e11821. doi: 10.1590/1414-431X2021e11821. 

  • Bernak-Oliveira Â, Guizoni DM, Chiavegatto S, Davel AP, Rossoni LV. The protective role of neuronal nitric oxide synthase in endothelial vasodilation in chronic β-adrenoceptor overstimulation. Life Sci. 2021 Nov 15;285:119939. doi: 10.1016/j.lfs.2021.119939.  

  • Sousa AS, Sponton ACS, Delbin MA. Perivascular adipose tissue and microvascular endothelial dysfunction in obese mice: Beneficial effects of aerobic exercise in adiponectin receptor (AdipoR1) and peNOSSer1177. Clin Exp Pharmacol Physiol. 2021 Oct;48(10):1430-1440. doi: 10.1111/1440-1681.13550.

  • Victorio JA, Guizoni DM, Freitas IN, Araujo TR, Davel AP. Effects of High-Fat and High-Fat/High-Sucrose Diet-Induced Obesity on PVAT Modulation of Vascular Function in Male and Female Mice. Front Pharmacol. 2021 Sep 10;12:720224. doi: 10.3389/fphar.2021.720224. 

  • Peres Valgas da Silva C, Calmasini F, Alexandre EC, Raposo HF, Delbin MA, Monica FZ, Zanesco A. The effects of mirabegron on obesity-induced inflammation and insulin resistance are associated with brown adipose tissue activation but not beiging in the subcutaneous white adipose tissue. Clinical and Experimental Pharmacology & Physiology, Aug 2021.doi: 10.1111/1440-1681.13566.
     
  • de Oliveira HT, Couto GK, Davel AP, Xavier FE, Rossoni LV. Chronic cyclooxygenase-2 inhibition prevents the worsening of hypertension and endothelial dysfunction induced by ouabain in resistance arteries of spontaneously hypertensive rats. Vascular Pharmacology, Aug 2021. doi: 10.1016/j.vph.2021.106880.
     
  • Sousa  AS, Sponton ACS, Delbin, MA. Perivascular adipose tissue and microvascular endothelial dysfunction in obese mice: Beneficial effects of aerobic exercise in adiponectin receptor (AdipoR1) and peNOS Ser1177. Clinical and Experimental Pharmacology & Physiology, 2021. doi: 10.1111/1440-1681.13550.
     
  • García-Arévalo M, Lorza-Gil E, Cardoso L, Batista TM, Araujo TR, Ramos LAF, Areas MA, Nadal A, Carneiro EM, Davel AP. Ventricular Fibrosis and Coronary Remodeling Following Short-Term Exposure of Healthy and Malnourished Mice to Bisphenol A. Frontiers in Physiology, Apr 2021. doi: 10.3389/fphys.2021.638506.
     
  • Feriani DJ, Sousa AS, Delbin MA, Ruberti OM, Crestani CC, Rodrigues B. Spleen tissue changes after restraint stress: effects of aerobic exercise training. Stress, Abr 2021. doi: 10.1080/10253890.2021.1895112. 
     
  • Ruberti OM, Sousa AS, Viana LR, Pereira Gomes MF, Medeiros A, Gomes Marcondes MCC, Borges LF, Crestani CC, Mostarda C, Moraes TFDC, Canevarolo RR, Delbin MA, Rodrigues B. Aerobic training prevents cardiometabolic changes triggered by myocardial infarction in ovariectomized rats. Journal of Cellular Physiology, Feb 2021. doi: 10.1002/jcp.29919
     
  • Wanschel ACBA, Guizoni DM, Lorza-Gil E, Salerno AG, Paiva AA, Dorighello GG, Davel AP, Balkan W, Hare JM, Oliveira HCF. The Presence of Cholesteryl Ester Transfer Protein (CETP) in Endothelial Cells Generates Vascular Oxidative Stress and Endothelial Dysfunction. Biomolecules, jan 2021. doi: 10.3390/biom11010069.
     
  • Guizoni DM, Freitas IN, Victorio JA, Possebom IR, Araujo TR, Carneiro EM, Davel AP. Taurine treatment reverses protein malnutrition-induced endothelial dysfunction of the pancreatic vasculature: the role of hydrogen sulfide. Metabolism-Clinical and Experimental, v. Jan, p. 154701, 2021. doi: 10.1016/j.metabol.2021.154701.
     
  • Victorio JA, da Costa RM, Tostes RC, Davel AP. Modulation of Vascular Function by Perivascular Adipose Tissue: Sex Differences. Curr Pharm Des. 2020 Jul 1. doi: 10.2174/1381612826666200701211912.
     
  • Guizoni DM, Vettorazzi JF, Carneiro EM, Davel AP. Modulation of endothelium-derived nitric oxide production and activity by taurine and taurine-conjugated bile acids. Nitric Oxide. 2020 Jan 1;94:48-53. doi:10.1016/j.niox.2019.10.008.
     
  • Lu Q, Davel AP, McGraw AP, Rao SP, Newfell BG, Jaffe IZ. PKCδ Mediates Mineralocorticoid Receptor Activation by Angiotensin II to Modulate Smooth Muscle Cell Function. Endocrinology, Sep 2019, doi: 10.1210/en.2019-00258. 
     
  • Sousa AS, Sponton ACS, Trifone CB, Delbin MA. Aerobic Exercise Training Prevents Perivascular Adipose Tissue-Induced Endothelial Dysfunction in Thoracic Aorta of Obese Mice. Front Physiol. 2019 Aug 16;10:1009. doi: 10.3389/fphys.2019.01009.
     
  • Victorio JA, Davel AP. Perivascular Adipose Tissue Oxidative Stress On The Pathophysiology Of Cardiometabolic Diseases. Curr Hypertens Rev. 2019 Apr 10. doi: 10.2174/1573402115666190410153634. 
     
  • Davel AP, Jaffe IZ, Tostes RC, Jaisser F, Belin de Chantemèle EJ. New roles of aldosterone and mineralocorticoid receptors in cardiovascular disease:translational and sex-specific effects. Am J Physiol Heart Circ Physiol. 2018 Oct 1;315(4):H989-H999. doi: 10.1152/ajpheart.00073.2018.
     
  • Baltieri N, Guizoni DM, Victorio JA, Davel AP. Protective Role of Perivascular Adipose Tissue in Endothelial Dysfunction and Insulin-Induced Vasodilatation of Hypercholesterolemic LDL Receptor-Deficient Mice. Front Physiol. 2018 Mar 19;9:229. doi: 10.3389/fphys.2018.00229.
     
  • Davel AP, Lu Q, Moss ME, Rao S, Anwar IJ, DuPont JJ, Jaffe IZ. Sex-Specific Mechanisms of Resistance Vessel Endothelial Dysfunction Induced by Cardiometabolic Risk Factors. J Am Heart Assoc. 2018 Feb 16;7(4). pii: e007675. doi: 10.1161/JAHA.117.007675.
     
  • Araujo HN, Victório JA, Valgas da Silva CP, Sponton ACS, Vettorazzi JF, de Moraes C, Davel AP, Zanesco A, Delbin MA. Anti-contractile effects of perivascular adipose tissue in thoracic aorta from rats fed a high-fat diet: role of aerobic exercise training. Clin Exp Pharmacol Physiol. 2018 Mar;45(3):293-302. doi: 10.1111/1440-1681.12882.
     
  • Sponton AC, Silva FH, Araujo HN, Valgas da Silva CP, de Moraes C, Antunes E, Zanesco A, Delbin MA. Circulating Concentrations of Adipocytokines and Their Receptors in the Isolated Corpus Cavernosum and Femoral Artery from Trained Rats on a High-Fat Diet. J Vasc Res. 2017;54(1):33-50. doi: 10.1159/000457800.  
     
  • da Silva Franco N, Lubaczeuski C, Guizoni DM, Victorio JA, Santos-Silva JC, Brum PC, Carneiro EM, Davel AP. Propranolol treatment lowers blood pressure, reduces vascular inflammatory markers and improves endothelial function in obese mice. Pharmacol Res. 2017 Aug;122:35-45. doi:10.1016/j.phrs.2017.05.018.
     
  • Davel AP, Anwar IJ, Jaffe IZ. The endothelial mineralocorticoid receptor: mediator of the switch from vascular health to disease. Curr Opin Nephrol Hypertens. 2017 Mar;26(2):97-104. doi: 10.1097/MNH.0000000000000306.
     
  • DuPont JJ, McCurley A, Davel AP, McCarthy J, Bender SB, Hong K, Yang Y, Yoo JK, Aronovitz M, Baur WE, Christou DD, Hill MA, Jaffe IZ. Vascular mineralocorticoid receptor regulates microRNA-155 to promote vasoconstriction and rising blood pressure with aging. JCI Insight. 2016 Sep 8;1(14):e88942. doi: 10.1172/jci.insight.88942.
     
  • Victorio JA, Fontes MT, Rossoni LV, Davel AP. Different Anti-Contractile Function and Nitric Oxide Production of Thoracic and Abdominal Perivascular Adipose Tissues. Front Physiol. 2016 Jul 12;7:295. doi: 10.3389/fphys.2016.00295.
     
  • Guizoni DM, Dorighello GG, Oliveira HC, Delbin MA, Krieger MH, Davel AP. Aerobic exercise training protects against endothelial dysfunction by increasing nitric oxide and hydrogen peroxide production in LDL receptor-deficient mice. J Transl Med. 2016 Jul 19;14(1):213. doi: 10.1186/s12967-016-0972-z.
     
  • Victorio JA, Clerici SP, Palacios R, Alonso MJ, Vassallo DV, Jaffe IZ, Rossoni LV, Davel AP. Spironolactone Prevents Endothelial Nitric Oxide Synthase Uncoupling and Vascular Dysfunction Induced by β-Adrenergic Overstimulation: Role of Perivascular Adipose Tissue. Hypertension. 2016 Sep;68(3):726-35. doi: 10.1161/HYPERTENSIONAHA.116.07911.
     
  • Davel AP, Victorio JA, Delbin MA, Fukuda LE, Rossoni LV. Enhanced endothelium-dependent relaxation of rat pulmonary artery following β-adrenergic overstimulation: involvement of the NO/cGMP/VASP pathway. Life Sci. 2015 Mar 15;125:49-56. doi: 10.1016/j.lfs.2015.01.018.
     
  • Araujo HN, Valgas da Silva CP, Sponton AC, Clerici SP, Davel AP, Antunes E, Zanesco A, Delbin MA. Perivascular adipose tissue and vascular responses in healthy trained rats. Life Sci. 2015 Mar 15;125:79-87. doi: 10.1016/j.lfs.2014.12.032.
     
  • Anaruma CP, Ferreira M Jr, Sponton CH, Delbin MA, Zanesco A. Heart rate variability and plasma biomarkers in patients with type 1 diabetes mellitus: Effect of a bout of aerobic exercise. Diabetes Res Clin Pract. 2016 Jan;111:19-27. doi: 10.1016/j.diabres.2015.10.025. 
     
  • Delbin MA, Trask AJ. The diabetic vasculature: physiological mechanisms of dysfunction and influence of aerobic exercise training in animal models.  Life Sci. 2014 Apr 25;102(1):1-9. doi: 10.1016/j.lfs.2014.02.021.