Agenda IB
Marcelo Alves da Silva Mori
The main purpose of our lab is to identify and characterize molecular mechanisms involved in the aging process and in response to dietary interventions. We pay particular interest to understand how metabolism contributes to the genesis of age-related diseases like type 2 diabetes, cardiovascular diseases, and neurodegenerative diseases. We focus on the fat tissue - an important site of metabolic integration in multicellular organisms - and ask ourselves how this tissue responds to changes in energy balance and signals to other tissues to inform them about these changes.
Paulo Guimarães Gandra
Our primary research interest is the investigation of cellular mechanisms regulating skeletal muscle contractile activity and energy metabolism during stimulation and fatigue.
In our lab we are employing an intact single skeletal muscle fiber model that allows us to measure force generation and perform fluorescence microscopy to analyze intracellular parameters in real time during contractions at a single cell level.
Andre Rinaldo Senna Garraffoni
Our research aims to study zoological taxa, such as Gastrotricha, Tardigrada, Kinorhyncha and Rotifera (also know as lesser-known protostome taxa) in oder to better understand the distinct evolutionary and biogeographical aspects of these freshwater and marine meiofauna organisms. Our ideia is integrate the distinct dimensions of meiofauna biodiversity - genetics, function, and phylogeny -based on in a broad framework that permits us to explore taxonomy, biogeography, molecular biology and evolutionary history