My main research area is the study of genetic diversity in different biological systems, its use and applications in plant breeding, conservation of wild species and new biotechnological targets in fungi for biomass degradation. These studies have been carried out mainly through molecular biology approaches, genetic and genomic analyses, biotechnology, computational biology, bioinformatics and statistical genetic tools.
The main purpose of our lab is to recognize the effects of multiparity and ageing in cells and extracellular matrix during postpartum recovery at birth canal (pubic symphysis, uterine cervix and vagina) in mice. We pay particular interest to understand how birth and ageing have a significant effect in tissue homeostasis, which could help us to understand the pathophysiology of pelvic organ prolapse, urinary incontinence and preterm. We focus on the connective tissue - an important site of cellular, molecular and hormonal signaling - and ask how this tissue responds (or not) to changes during and after first and multiple pregnancies. Using morphological, biochemical and molecular assays, we identified that recovery processes are regulated by cells and molecules in the birth canal and multiparity and ageing led them to not recover in the reproductive matrix mice.
Translational research in Tropical diseases, with an emphasis on understanding the immunopathological aspects of Malaria, as well as the discovery of new drugs.